1. Kao C, Wang SW, Chen PC, Huang CY, Wei YF, Ho CH, Hong YH. Rice Husk Silica Liquid Enhances Autophagy and Reduces Overactive Immune Responses via TLR-7 Signaling in Lupus-Prone Models. Int J Mol Sci. 2024 Sep 21;25(18):10133. (IF= 4.9, Rank= BIOCHEMISTRY & MOLECULAR BIOLOGY, 72/319=22.6%).
  2. Lee KT, Lin CY, Liu SC, He XY, Tsai CH, Ko CY, Tsai YH, Chao CC, Chen PC*, Tang CH*. IL-17 promotes IL-18 production via the MEK/ERK/miR-4492 axis in osteoarthritis synovial fibroblasts. Aging (Albany NY). (2024 Jan 22);16(2):1829-44. 本人為共同通訊作者
  3. Chao CC, Hsiao SY, Kao WC, Chiou PC, Huang CC, Wang MT*, Chen PC*. Pyrroloquinoline quinone ameliorates PM2.5-induced pulmonary fibrosis through targeting epithelial-mesenchymal transition. J Cell Mol Med. (2024 Apr);28(8):e18299. (IF= ˋˋ4.2, Rank= MEDICINE, GENERAL & INTERNAL, 56/195=28.7%). 本人為共同通訊作者
  4. Jiang YJ, Ho TL, Chao CC, He XY, Chen PC, Cheng FJ, Huang WC, Huang CL, Liu PI, Tang CH. Particulate matter facilitates amphiregulin-dependent lung cancer proliferation through glutamine metabolism. Int J Biol Sci. 2024 May 27;20(8):3126-3139. (IF= 10.0, Rank= BIOCHEMISTRY & MOLECULAR BIOLOGY, 26/319=8.2%).
  5. Tsai TF, Hwang TI, Chen PC, Chen YC, Chou KY, Ho CY, Chen HE, Chang AC. Hyperthermia reduces cancer cell invasion and combats chemoresistance and immune evasion in human bladder cancer. Int J Oncol. 2024 Dec;65(6):116. (IF= 4.9, Rank= ONCOLOGY, 73/326=22.4%).
  6. Chen PC, Chen WH, Lien LM, Chou CC, Chao CC, Bai CH. Association of IL-18 gene polymorphisms with clinical aspects of hyperlipidemia in middle-aged and early people in the community. Int J Med Sci. (2024;21(6):1064-71. (IF= 3.2, Rank= MEDICINE, GENERAL & INTERNAL, 59/332=17.8%). 本人為第一作者
  7. Chen PC*, Yen MH, Hsiao SY, Kao WC, Wang MT*, Chiou PC, Chao CC. Melatonin prevents pulmonary fibrosis caused by PM(2.5) exposure by targeting epithelial-mesenchymal transition. Toxicol Appl Pharmacol. (2024 Jun);487:116949. (IF= 3.4, Rank= TOXICOLOGY, 34/106=32.1%). 本人為共同第一作者
  8. Chang EM, Chao CC, Wang MT, Hsu CL, Chen PC. PM(2.5) promotes pulmonary fibrosis by mitochondrial dysfunction. Environ Toxicol. (2023 Aug);38(8):1905-13. (IF= 3.2, Rank= TOXICOLOGY, 39/106=36.8%). 本人為共同通訊作者
  9. Hou CH, Chen PC*, Liu JF*. CXCL1 enhances COX-II expression in rheumatoid arthritis synovial fibroblasts by CXCR2, PLC, PKC, and NF-kappaB signal pathway. Int Immunopharmacol. (2023 Sep 16);124(Pt B):110909. (IF= 4.7, Rank= PHARMACOLOGY & PHARMACY, 54/352=15.3%). 本人為共同通訊作者
  10. Hwang TI, Cuiu YC, Chen YC, Chen PC, Tsai TF, Chou KY, Ho CY, Chen HE, Chang PH, Chang AC. Tumor suppressive functions of hsa‑miR‑34a on cell cycle, migration and protective autophagy in bladder cancer. Int J Oncol. (2023 May);62(5). (IF= 4.9, Rank= ONCOLOGY, 73/326=22.4%).
  11. Chang AC, Lin LW, Chen YC, Chen PC, Liu SC, Tai HC, Wu HC, Sung SY, Lin TH, Tang CH. The ADAM9/WISP-1 axis cooperates with osteoblasts to stimulate primary prostate tumor growth and metastasis. Int J Biol Sci. (2023 Jan);19(3):760-71. (SCI). (IF= 10.0, Rank= BIOCHEMISTRY & MOLECULAR BIOLOGY, 26/319=8.2%).
  12. Hwang TI*, Chen PC*, Tsai TF, Lin JF, Chou KY, Ho CY, Chen HE, Chang AC. Hsa-miR-30a-3p overcomes the acquired protective autophagy of bladder cancer in chemotherapy and suppresses tumor growth and muscle invasion. Cell Death Dis. (2022); 13(4): 390. (SCI). (IF= 9.6, Rank= CELL BIOLOGY, 29/204=14.2%). 本人為共同第一作者
  13. Liu JF*, Chen PC*, Ling TY, Hou CH. Hyperthermia increases HSP production in human PDMCs by stimulating ROS formation, p38 MAPK and Akt signaling, and increasing HSF1 activity. Stem Cell Res Ther. (2022); 13(1): 236 . (SCI). (IF= 7.3, Rank= CELL & TISSUE ENGINEERING, 3/32=9.4%). 本人為共同第一作者
  14. Hsiao SY, Tang CH, Chen PC, Lin TH, Chao CC. Melatonin Inhibits EMT in Bladder Cancer by Targeting Autophagy. Molecules. 2022 Dec 7;27(24):8649. (IF= ˋˋ4.6, Rank= BIOCHEMISTRY & MOLECULAR BIOLOGY, 82/319=25.7%).
  15. Tsai TF, Chang AC, Chen PC, Ho CY, Chen HE, Chou KY, Hwang TI. Autophagy blockade potentiates cancer-associated immunosuppression through programmed death ligand-1 upregulation in bladder cancer. J Cell Physiol. (2022); 237(9): 3587-3597. (SCI). (IF= 4.0, Rank= PHYSIOLOGY, 14/87=16.1%).
  16. Jiang YJ, Chao CC, Chang AC, Chen PC, Cheng FJ, Liu JF, Liu PI, Huang CL, Guo JH, Huang WC, Tang CH. Cigarette smoke-promoted increases in osteopontin expression attract mesenchymal stem cell recruitment and facilitate lung cancer metastasis. J Adv Res. (2022 Nov);41:77-87. (SCI). (IF= 13.0, Rank= MULTIDISCIPLINARY SCIENCES, 11/135=8.1%)
  17. Lin TH, Chang SL, Khanh PM, Trang NTN, Liu SC, Tsai HC, Chang AC, Lin JY, Chen PC, Liu JF, Guo JH, Liu CL, Wu HC, Tang CH. Apelin Promotes Prostate Cancer Metastasis by Downregulating TIMP2 via Increases in miR-106a-5p Expression. Cells. (2022); 11(20). (SCI). (IF= 5.2, Rank= CELL BIOLOGY, 59/204=28.9%)
  18. Chen, P.C., Liu, S.C., Lin, T.H., Lin, L.W., Wu, H.C., Tai, H.C., Wang, S.W., Tang, C.H. Prostate cancer-secreted CCN3 uses the GSK3beta and beta-catenin pathways to enhance osteogenic factor levels in osteoblasts. Environmental toxicology. (2021); 36(3): 425-432. (SCI). (IF= 4.119, Rank= WATER RESOURCES, 21/98). 本人為第一作者
  19. Ho, C.Y., Chang, A.C., Hsu, C.H., Tsai, T.F., Lin, Y.C., Chou, K.Y., Chen, H.E., Lin, J.F., Chen, P.C.*, Hwang, T.I.* Miconazole induces protective autophagy in bladder cancer cells. Environmental toxicology. (2021); 36(2): 185-193. (SCI). (IF= 4.119, Rank= WATER RESOURCES, 21/98). 本人為通訊作者
  20. Chou, K.Y., Chang, A.C., Tsai, T.F., Lin, Y.C., Chen, H.E., Ho, C.Y., Chen, P.C.*, Hwang, T.I.* MicroRNA34a5p serves as a tumor suppressor by regulating the cell motility of bladder cancer cells through matrix metalloproteinase2 silencing. Oncology reports. (2021); 45(3): 911-920. (SCI). (IF= 3.906, Rank= ONCOLOGY, 133/242). 本人為通訊作者
  21. Liu, P.I., Chang, A.C., Lai, J.L., Lin, T.H., Tsai, C.H., Chen, P.C., Jiang, Y.J., Lin, L.W., Huang, W.C., Yang, S.F., Tang, C.H. Melatonin interrupts osteoclast functioning and suppresses tumor-secreted RANKL expression: implications for bone metastases. Oncogene. (2021); 40(8): 1503-1515. (SCI). (IF= 9.867, Rank= GENETICS & HEREDITY, 12/175).
  22. K.Y. Chou, A.C. Chang, C.Y. Ho, T.F. Tsai, H.E. Chen, P.C. Chen* and T.I. Hwang*. Thrombospondin-4 promotes bladder cancer cell migration and invasion via MMP2 production. J Cell Mol Med. 2021. (SCI). (IF= 5.310, Rank= MEDICINE, RESEARCH & EXPERIMENTAL, 44/140) 本人為通訊作者
  23. Wang, S.W., Tai, H.C., Tang, C.H., Lin, L.W., Lin, T.H., Chang, A.C., Chen, P.C., Chen, Y.H., Wang, P.C., Lai, Y.W., Chen, S.S. Melatonin impedes prostate cancer metastasis by suppressing MMP-13 expression. Journal of cellular physiology. (2021); 236(5): 3979-3990. (SCI). (IF= 6.384, Rank= PHYSIOLOGY, 7/81).
  24. Hou, C.H., Tang, C.H., Chen, P.C.*, Liu, J.F.* Thrombospondin 2 Promotes IL-6 Production in Osteoarthritis Synovial Fibroblasts via the PI3K/AKT/NF-kappaB Pathway. J Inflamm Res. (2021); 14: 5955-5967. (SCI). (IF= 6.922, Rank= IMMUNOLOGY, 35/162). 本人為通訊作者
  25. Tsai, C.H., Chen, C.J., Gong, C.L., Liu, S.C., Chen, P.C., Huang, C.C., Hu, S.L., Wang, S.W., Tang, C.H. CXCL13/CXCR5 axis facilitates endothelial progenitor cell homing and angiogenesis during rheumatoid arthritis progression. Cell Death Dis. (2021); 12(9): 846. (SCI). (IF= 9.696, Rank= CELL BIOLOGY, 36/195)
  26. Chao, C.C., Lee, W.F., Wang, S.W., Chen, P.C., Yamamoto, A., Chang, T.M., Weng, S.L., Liu, J.F. CXC chemokine ligand-13 promotes metastasis via CXCR5-dependent signaling pathway in non-small cell lung cancer. J Cell Mol Med. (2021); 25(19): 9128-9140. (SCI). (IF= 5.310, Rank= MEDICINE, RESEARCH & EXPERIMENTAL, 44/140)
  27. Chou, K.Y.*, Chen, P.C.*, Chang, A.C., Tsai, T.F., Chen, H.E., Ho, C.Y., Hwang, T.I. Attenuation of chloroquine and hydroxychloroquine on the invasive potential of bladder cancer through targeting matrix metalloproteinase 2 expression. Environmental toxicology. (2021); 36(11): 2138-2145. (SCI). (IF= 4.119, Rank= WATER RESOURCES, 21/98). 本人為第一作者
  28. Chao, C.C., Lee, C.W., Chang, T.M., Chen, P.C., Liu, J.F. CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma. Cancers (Basel). (2020); 12(2). (SCI). (IF= 6.639, Rank= ONCOLOGY, 51/242)
  29. Tsai, T.F., Chen, P.C.*, Lin, Y.C., Chou, K.Y., Chen, H.E., Ho, C.Y., Lin, J.F., Hwang, T.I.* Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells. Drug Des Devel Ther. (2020); 14: 1209-1218. (SCI). (IF= 4.162, Rank= PHARMACOLOGY & PHARMACY, 100/275). 本人為通訊作者
  30. Tsai, T.F., Chen, P.C., Lin, Y.C., Chou, K.Y., Chen, H.E., Ho, C.Y., Lin, J.F., Hwang, T.I. Benzyl isothiocyanate promotes miR-99a expression through ERK/AP-1-dependent pathway in bladder cancer cells. Environmental toxicology. (2020); 35(1): 47-54. (SCI). (IF= 4.119, Rank= WATER RESOURCES, 21/98).
  31. Liu, J.F., Chen, P.C., Chang, T.M., Hou, C.H. Monocyte Chemoattractant Protein-1 promotes cancer cell migration via c-Raf/MAPK/AP-1 pathway and MMP-9 production in osteosarcoma. J Exp Clin Cancer Res. (2020); 39(1): 254. (SCI). (IF= 11.161, Rank= ONCOLOGY, 25/242)
  32. Liu, J.F., Chen, P.C., Chang, T.M., Hou, C.H. Thrombospondin-2 stimulates MMP-9 production and promotes osteosarcoma metastasis via the PLC, PKC, c-Src and NF-kappaB activation. J Cell Mol Med. (2020); 24(21): 12826-12839. (SCI). (IF= 5.310, Rank= MEDICINE, RESEARCH & EXPERIMENTAL, 44/140)
  33. Hou, S.M., Chen, P.C., Lin, C.M., Fang, M.L., Chi, M.C., Liu, J.F. CXCL1 contributes to IL-6 expression in osteoarthritis and rheumatoid arthritis synovial fibroblasts by CXCR2, c-Raf, MAPK, and AP-1 pathway. Arthritis research & therapy. (2020); 22(1): 251. (SCI). (IF= 5.156, Rank= RHEUMATOLOGY, 9/34)
  34. Yang, Y.C., Chiou, P.C., Chen, P.C., Liu, P.Y., Huang, W.C., Chao, C.C., Tang, C.H. Melatonin reduces lung cancer stemness through inhibiting of PLC, ERK, p38, beta-catenin, and Twist pathways. Environmental toxicology. (2019); 34(2): 203-209. (IF= 4.119, Rank= WATER RESOURCES, 21/98)
  35. Chao, C.C.*, Chen, P.C.*, Chiou, P.C., Hsu, C.J., Liu, P.I., Yang, Y.C., Reiter, R.J., Yang, S.F., Tang, C.H. Melatonin suppresses lung cancer metastasis by inhibition of epithelial-mesenchymal transition through targeting to Twist. Clinical science. (2019); 133(5): 709-722. (SCI). (IF= 6.124, Rank= MEDICINE, RESEARCH & EXPERIMENTAL, 31/140). 本人為第一作者
  36. Tsai, T.F., Lin, J.F., Lin, Y.C., Chou, K.Y., Chen, H.E., Ho, C.Y., Chen, P.C.*, Hwang, T.I.* Cisplatin contributes to programmed death-ligand 1 expression in bladder cancer through ERK1/2-AP-1 signaling pathway. Bioscience reports. (2019); 39(9). (SCI). (IF= 3.840, Rank= BIOCHEMISTRY & MOLECULAR BIOLOGY, 153/297). 本人為通訊作者
  37. Chen, P.C., Liu, J.F., Fong, Y.C., Huang, Y.L., Chao, C.C., Tang, C.H. CCN3 Facilitates Runx2 and Osterix Expression by Inhibiting miR-608 through PI3K/Akt Signaling in Osteoblasts. International journal of molecular sciences. (2019); 20(13). (SCI). (IF= 6.208, Rank= BIOCHEMISTRY & MOLECULAR BIOLOGY, 69/297). 本人為第一作者
  38. Wang, M.*, Chao, C.C.*, Chen, P.C.*, Liu, P.I., Yang, Y.C., Su, C.M., Huang, W.C., Tang, C.H. Thrombospondin enhances RANKL-dependent osteoclastogenesis and facilitates lung cancer bone metastasis. Biochemical pharmacology. (2019); 166: 23-32. (SCI). (IF= 5.858, Rank= PHARMACOLOGY & PHARMACY, 39/275). 本人為第一作者
  39. Hou, C.H., Tang, C.H., Chen, P.C., Liu, J.F. Thrombospondin 2 Promotes IL-6 Production in Osteoarthritis Synovial Fibroblasts via the PI3K/AKT/NF-kappaB Pathway. J Inflamm Res. (2021); 14: 5955-5967. (IF= 6.922, Rank= IMMUNOLOGY, 35/162). 本人為通訊作者

  1. M. L. Hsu, P. C. Chen, C. H. Hou. ENTERODIOL AND ENTEROLACTONE INHIBIT RANKL-INDUCED OSTEOCLASTOGENESIS BY REGULATING PGC-1Β/ERRⱭ MEDIATED MITOCHONDRIAL BIOGENESIS. World congress on osteoporosis, osteoarthritis and musculoskeletal diseases. (2025)
  2. Chun-Han Hou, Po-Chun Chen. The lignans metabolites, enterolactone and enterodiol, prevent osteoclast differentiation by Akt signal pathway. World congress on osteoporosis, osteoarthritis and musculoskeletal diseases. (2024)

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