1. Su MT*, Jheng YS, Lu CW, Wu WJ, Yang SY, Chuang WC, Lee MC, Wu CH (2022) Neurotherapy of Yi-Gan-San, a Traditional Herbal Medicine, in an Alzheimer's Disease Model of Drosophila melanogaster by Alleviating Abeta42 Expression. Plants (Basel) 11 (4). doi:10.3390/plants11040572
  2. Deng N, Wu YY, Feng Y, Hsieh WC, Song JS, Lin YS, Tseng YH, Liao WJ, Chu YF, Liu YC, Chang EC, Liu CR, Sheu SY, Su MT, Kuo HC, Cohen SN, Cheng TH (2022) Chemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes. Proc Natl Acad Sci U S A 119 (32):e2204779119. doi:10.1073/pnas.2204779119
  3. Chiu YJ, Lin TH, Chen CM, Lin CH, Teng YS, Lin CY, Sun YC, Hsieh-Li HM, Su MT, Lee-Chen GJ, Lin W, Chang KH (2021) Novel Synthetic Coumarin-Chalcone Derivative (E)-3-(3-(4-(Dimethylamino)Phenyl)Acryloyl)-4-Hydroxy-2H-Chromen-2-One Activates CREB-Mediated Neuroprotection in Abeta and Tau Cell Models of Alzheimer's Disease. Oxid Med Cell Longev 2021:3058861. doi:10.1155/2021/3058861
  4. Huang CC, Chang KH, Chiu YJ, Chen YR, Lung TH, Hsieh-Li HM, Su MT, Sun YC, Chen CM, Lin W, Lee-Chen GJ (2021) Multi-Target Effects of Novel Synthetic Coumarin Derivatives Protecting Abeta-GFP SH-SY5Y Cells against Abeta Toxicity. Cells 10 (11). doi:10.3390/cells10113095
  5. Chiang NN, Lin TH, Teng YS, Sun YC, Chang KH, Lin CY, Hsieh-Li HM, Su MT, Chen CM, Lee-Chen GJ (2021) Flavones 7,8-DHF, Quercetin, and Apigenin Against Tau Toxicity via Activation of TRKB Signaling in DeltaK280 TauRD-DsRed SH-SY5Y Cells. Front Aging Neurosci 13:758895. doi:10.3389/fnagi.2021.758895
  6. Lee LC, Su MT, Huang HY, Cho YC, Yeh TK, Chang CY (2021) Association of CaMK2A and MeCP2 signaling pathways with cognitive ability in adolescents. Mol Brain 14 (1):152. doi:10.1186/s13041-021-00858-8
  7. Fan CH, Lin CW, Huang HJ, Lee-Chen GJ, Sun YC, Lin W, Chen CM, Chang KH, Su MT*, Hsieh-Li HM (2020) LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer's disease. Psychopharmacology (Berl) 237 (10):3173-3190. doi:10.1007/s00213-020-05602-z
  8. Chen CM, Lin CH, Wu YR, Yen CY, Huang YT, Lin JL, Lin CY, Chen WL, Chao CY, Lee-Chen GJ, Su MT*, Chang KH (2020) Lactulose and Melibiose Inhibit alpha-Synuclein Aggregation and Up-Regulate Autophagy to Reduce Neuronal Vulnerability. Cells 9 (5). doi:10.3390/cells9051230
  9. Huang HJ, Chen SL, Huang HY, Sun YC, Lee GC, Lee-Chen GJ, Hsieh-Li HM, Su MT* (2019) Chronic low dose of AM404 ameliorates the cognitive impairment and pathological features in hyperglycemic 3xTg-AD mice. Psychopharmacology (Berl) 236 (2):763-773. doi:10.1007/s00213-018-5108-0
  10. Chen CM, Chen WL, Hung CT, Lin TH, Chao CY, Lin CH, Wu YR, Chang KH, Yao CF, Lee-Chen GJ, Su MT*, Hsieh-Li HM (2018) The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 mice. Neurotoxicology 67:259-269. doi:10.1016/j.neuro.2018.06.009
  11. Lee LC, Su MT, Cho YC, Lee-Chen GJ, Yeh TK, Chang CY (2019) Multiple epigenetic biomarkers for evaluation of students' academic performance. Genes Brain Behav 18 (5):e12559. doi:10.1111/gbb.12559
  12. Hsu, T.C., Wang, C.K., Yang, C.Y., Lee, L.C., Hsieh-Li, H.M., Lo, L.S., Chen, C.M., Lee-Chen, G.J. and Su, M.T. (2014) Deactivation of TBP Contributes to SCA17 Pathogenesis Hum Mol Genet, in press., Epub ahead of print.

  1. TBP deactivation activates JNK mediated oxidative stress

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PPP2R2B在神經退化性疾病的功能研究--以果蠅為模式研究PPP2R2B 在神經發育的功能及其與退化性神經疾病的關連 2006/06/08 2008/07/31 國科會 95-2311-B-003-006-MY2 主持人