1. Therapeutic Potential of Bioactive Peptides Derived from Natural Products of Tortoiseshell and Antler in Alleviating Osteoporosis and Osteoarthritis
  2. Daphnetin Protects Schwann Cells Against High-Glucose-Induced Oxidative Injury by Modulating the Nuclear Factor Erythroid 2-Related Factor 2/Glutamate–Cysteine Ligase Catalytic Subunit Signaling Pathway
  3. Chinese Herbal Medicines as Natural Alternative Products to Antibiotics in Weaned Piglets through Intestinal Microbiota Regulation
  4. Therapeutic Application of Dendrobium fimbriatum Hook for Retinopathy Caused by UV Radiation and Chemothera-py Using ARPE-19 Cells and Mouse Retina
  5. Prevalence and determinants of constipation in children in Asia: a systematic review and meta-analysis
  6. 2′-Hydroxycinnamaldehyde, a Natural Product from Cinnamon, Alleviates Ischemia/Reperfusion-Induced Microvascular Dysfunction and Oxidative Damage in Rats by Upregulating Cytosolic BAG3 and Nrf2/HO-1
  7. Pharmaceutical Screening of Bat Feces and Their Applica-tions and Risks in Traditional Chinese Medicine
  8. Neonicotinoid Imidacloprid Affects the Social Behavior of Adult Zebrafish by Damaging Telencephalon Neurons through Oxidation Stress, Inflammation, and Apoptosis
  9. Therapeutic Effects of Plant Extracts of Anoectochilus roxburghii on Alleviating Side Effects of Chemotherapy in Breast Cancer BALB/c mice
  10. Alleviative effect of Ficus formosana extract on peripher-al neuropathy in ovariectomized diabetic mice
  11. 蛹蟲草萃取物對於化療小鼠心肌損傷與骨質疏鬆的保護作用
  12. Lu CW, Nguyen NTK, Shen SC, Wu YB, Liang HJ, Wu CH*
  13. Su MT, Jheng YS, Lu CW, Wu WJ, Yang SY, Chuang WC, Lee MC, Wu CH* (2022) Neurotherapy of Yi-Gan-San, a Traditional Herbal Medicine, in an Alzheimer’s Disease Model of Drosophila melanogaster by Alleviating Aβ42 Expression. Plants 11(4):572.
  14. Su MT, Lu CW, Wu WJ, Jheng YS, Yang SY, Chuang WC, Lee MC, Wu CH*
  15. Wang CH, Wang SE, Wu WJ, Su LY, Lu CW, Wang PH, Lee MC, Chuang WC, Wu CH* (2021) Chinese herbal medicine Guizhi Li-Zhong Tang formula as an alternative antibiotic feed additives for alleviating pneumonia in piglets via antioxidant, anti-inflammatory, and anti-apoptotic protection. Evidence-Based Complementary and Alternative Medicine Volume 2021, Article ID 4978783
  16. MPTP toxicity causes vocal, auditory, orientation and movement defects in the echolocation bat
  17. Kimprasit T, Nunome M, Iida K, Murakami Y, Wong M-L, Wu CH, et al. (2021)Dispersal history of Miniopterus fuliginosus bats and their associated viruses in east Asia. PLoS ONE 16(1): e0244006.
  18. Wu CH*, Lu CW, Hsu TH, Wu WJ, Wang SE (2021) Neurotoxicity of fipronil affects sensory and motor systems in zebrafish. Pesticide Biochemistry and Physiology 177: 104896
  19. Lu CW, Belashov A, Zhikhoreva A, Semenova I, Cheng C J, Su L Y, Wu CH* (2021) Application of digital holographic tomography in antitumor effect of cantharides complex on 4T1 breast cancer cells. Applied Optics 60(12): 3365-3373
  20. Lien CY, Lu CW, Lin YH, WuW J, Hsu CH, Chuang TY, Lin KF, Chuang WC, Lee MC, Wu CH* (2021) Chinese Herbal Medicine, Guilu Erxian Glue, as alternative medicine for adverse side effects of chemotherapy in doxorubicin-treated cell and mouse models. Evidence-Based Complementary and Alternative Medicine Volume 2021, Article ID 5548968,
  21. Wu WJ, Lu CW, Wang SE, Lin CL, Su LY, Wu CH* (2021) MPTP toxicity causes vocal, auditory, orientation, and movement defects in the echolocation bat. Neuroreport 32:125-134 (SCI) PMID: 33323836/ DOI: 10.1097/WNR.0000000000001574.
  22. Yeh CW, Wu WJ, Su LY, Lu CW, Wang SE, Lee MC, Chuang WC, Wu CH* (2021) Traditional Chinese Medicine Yang-Gan-Wan Alleviated Experimental Hepatic Damage by Inhibiting Oxidation, Inflammation, and Apoptosis in Cell and Mouse Models. Evidence-Based Complementary and Alternative Medicine Volume 2021, Article ID 2556352
  23. Wang SE, Wu CH* (2021) Tau phosphorylation and cochlear apoptosis cause hearing loss in 3×Tg-AD mouse model of Alzheimer's disease. Chinese Journal of Physiology 64:61-71
  24. Lu CW, Wang SE, Wu WJ, Su LY, Wang CH, Wang PH, Wu CH* (2021) Alternative antibiotic feed additives alleviate pneumonia with inhibiting ACE‐2 expression in the respiratory system of piglets. Food Science & Nutrition 9:1112–1120.
  25. Chuang TY, Lien CY, Tsai YC, Lin KF, Hsu CH, Wu WJ, Su LY, Lu CW, Wu CH* (2020) Oral treatment with the Chinese herbal supplements B307 enhances muscle endurance of ICR mice after exhaustive swimming via suppressing fatigue, oxidative stress, and inflammation. Food Science & Nutrition 8:3682–3691.n.
  26. Chinese Herbal Medicine Alleviates Thyroidectomy-Induced Cardiopulmonary Exercise Dysfunction in Rats
  27. Wu CH*, Lin CL, Wang SE, Lu CW (2020) Effects of imidacloprid, a neonicotinoid insecticide, on the echolocation system of insectivorous bats. Pesticide Biochemistry and Physiology 163:94-101.
  28. Lien CY, Lu CW, Hsu CH, Chuang TY, Su LY, Wu WJ, Jheng YS, Lee MC, Wu CH* (2020) Chinese veterinary medicine B307 promotes cardiac performance and skeletal muscle contraction via enhancing intracellular calcium levels and neural electrical activity in animal and cell models. Evidence-Based Complementary and Alternative Medicine Volume 2020, Article ID 9064824.
  29. Doysabasa KC,.., Wu CH, .., Hondo E* (2019) Encephalomyocarditis virus is potentially derived from eastern bent-wing bats living in East Asian countries. Virus Research 259: 62–67.
  30. Wu CH*, Wang SE, Hsu CH, Hsu YT, Lu CW, Chuang WC, Lee MC (2019) Reproductive regulation and oxidative stress alleviation of Chinese herbal medicine therapy in ovariectomised mouse model. Evidence-Based Complementary and Alternative Medicine Volume 2019, Article ID 5346518
  31. Chung KT, Hsu CH, Lin, Hsu CH, Wang SE, Wu CH* (2018) Traditional Chinese herbal formula relieves snoring through modulating activities of upper airway related nerves in aged rats. Drug Design, Development and Therapy 12: 1165–1171.
  32. L-Theanine Inhibits Proinflammatory PKC/ERK/ICAM-1/ IL-33 Signaling, Apoptosis, and Autophagy Formation in Substance P-Induced Hyperactive Bladder in Rats
  33. Protective Effects of Wogonin against Alzheimer's Disease by Inhibition of Amyloidogenic Pathway
  34. Lu CW, Hsiao JK, Liu HM*, Wu CH* (2017) Characterization of an an iron oxide nanoparticle labeling and MRI -based protocol for inducing human mesenchymal stem cells into neural-like cells. Scientific Reports 7: 3587, DOI:10.1038/s41598-017-03863-x.
  35. Hypothermic neuroprotections in the brain of an echolocation
  36. The potential of synthetic indolylquinoline derivatives for Aβ aggregation reduction by chemical chaperone activity
  37. Hsu CH,Wang SE, Lin CL, Hsiao CJ, Sheu SJ, Wu CH. (2016). Neuroprotective Effects of the Herbal Formula B401 in Both Cell and Mouse Models of Alzheimer’s Disease. Evidence-Based Complementary andAlternativeMedicine, 2016, 17.
  38. Hsu CH, Wang SE, Lin CL, Sheu SJ, Wu CH. (2016). Remission roles of the herbal formula B401 in mice with manganese-induced neurotoxicity. Botanics: Targets and Therapy, 6, 75-88.
  39. Hsiao CJ, Hsu CH, Lin CL, Wu CH, Jen PHS. (2016). Comparisons of MRI images, and auditory and vocal related protein expressions in the brain of echolocation bats and rodents. Neuroreport, 27(12), 923-928.
  40. Huang DS, Lin HY, Lee-Chen GJ, Hsieh-Lee HM, Wu CH*, Lin JY*, 2016, Treatment with a Ginkgo biloba extract, EGb 761 inhibits excitotoxicity in an animal model of spinocerebellar ataxia type 17. Drug Design, Development and Therapy, 10, 723-731.
  41. Hsiao CJ, Lin CL, Lin TY, Wang SE, Wu CH. (2016). Imidacloprid toxicity impairs spatial memory of echolocation bats via neural apoptosis in hippocampal CA1 and medial entorhinal cortex areas. Neuro Report, 27(6), 462-468.
  42. Tsai WH, Wu CH, Cheng CH, Chien CT. (2015). Ba-Wei-Di-Huang-Wan through its active ingredient loganin counteracts substance P-enhanced NF-κB/ICAM-1 signaling in rats with bladder hyperactivity. Neurourology and Urodynamics, 35(7), 771-779.
  43. Lin CL, Wang SE, Hsu CH, Sheu SJ, Wu CH. (2015). Oral treatment with herbal formula B307 alleviates cardiac failure in aging R6/2 mice with Huntington's disease via suppressing oxidative stress, inflammation and apoptosis. Clinical Interventions in Aging, 10, 1173-1187
  44. Wang SE, Lin CL, Hsu CH, Sheu SJ, Wu CH. (2015). Oral treatment with the herbal formula B401 protects against aging-dependent neurodegeneration by attenuating oxidative stress and apoptosis in the brain of R6/2 mice. Clinical Interventions in Aging, 10, 1825-1837.
  45. Hsiao CJ, Jen PH-S, Wu CH. (2015). The cochlear size of bats and rodents derived from magnetic resonance images and histology. Neuroreport, 26(8), 478-482.
  46. Wang SE, Wu CH. (2015), Physiological and histological evaluations of the cochlea between 3xTg-AD mouse model of Alzheimer's diseases and R6/2 mouse model of Huntington's disease. The Chinese Journal of Physiology, 58(6), 359-366.
  47. Lai XJ, Tu HY, Wu CH, Lin Y-C, Cheng CJ. (2015). Resolution enhancement of spectrum normalization in synthetic aperture digital holographic microscopy. Applied Optics, 54(1), A51-58.
  48. Jen PHS, Wu CH. (2015). Echo amplitude sensitivity of bat auditory neurons improves with decreasing pulse–echo gap. Neuroreport, 26(1), 38-43
  49. Lien CY, Chuang TY, Hsu CH, Lin CL, Wang SE, Sheu SJ, Chien CT, Wu CH. (2015). Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin- treated mice via suppressing oxidative stress, inflammation, and apoptosis. OncoTargets and Therapy, 8, 1193-1210.
  50. Wang SE, Lin CL, Hsu CH, Sheu SJ, Chien CT, Wu CH. (2015). Treatment with a herbal formula B401 enhances neuroprotection and angiogenesis in the R6/2 mouse model of Huntington's disease. Drug Design, Development and Therapy, 9, 887-900.
  51. Wu CH, Lai XJ, Cheng CJ, Yu YC, Chang CY. (2014). Applications of digital holographic microscopy in therapeutic evaluation of Chinese herbal medicines. Applied Optics, 53(27), G192-197.
  52. Kung PJ, Tao YC, Hsu HC, Chen WL, Lin TH, Janreddy D, Yao CF, Chang KH, Lin JY, Su MT, Wu CH, Lee-Chen GJ, Hsieh-Li HM. (2014). Indole and synthetic derivative activate chaperone expression to reduce polyQ aggregation in SCA17 neuronal cell and slice culture models. Drug Design Development and Therapy, 8, 1929-1939.
  53. Yeh TK, Hu CY, Yeh TC, Lin PJ, Wu CH, Lee PL, Chang CY. (2012). Association of polymorphisms in BDNF, MTHFR, and genes involved in the dopaminergic pathway with memory in a healthy Chinese population. Brain and Cognition, 80(2), 282-289.
  54. Jen P, Wu CH, Wang X. (2012). Dynamic temporal signal processing in the inferior colliculus of echolocating bats. Frontiers in Neural Circuits, 6, 27.
  55. Lee LC, Chen CM, Wang HC, Hsieh HH, Chiu IS, Su MT, Hsieh-Li HM, Wu CH, Lee GC, Lee-Chen GJ, Lin JY. (2012). Role of the CCAAT-Binding Protein NFY in SCA17 Pathogenesis. PLoS ONE, 7(4), e35302.
  56. Chuang TY, Ding ST, Wu CH. (2012). Effects of Aerobic Exercise Training in Early Stage R6/2 Huntington’s Disease Transgenic Mice. Journal of Exercise Physiology and Fitness, 15, 27-38.
  57. Chuang TY, Ding ST, Hung DS, Wu CH. (2011). Strengthened Aerobic Exercise Ability in Adiponectin R1 Transgenic Mice. Journal of Exercise Physiology and Fitness, 12, 41-50.
  58. Wu CH, Jen PH-S. (2010). A duration coding mechanism underlying bat echo recognition. Adaptive Medicine, 2(2), 71-77.
  59. Meena JS, Chu MC, Tiwari JN, You HC, Wu CH, Ko FH. (2010). Flexible metal-insulator-metal capacitor using plasma enhanced binary hafnium- zirconium-oxide as gate dielectric layer. Microelectronics and Reliability, 50, 652-656.
  60. 王雪娥、吳忠信。2010。治療聽覺異常的新思維。醫檢會刊，903，54-55。
  61. Lee LC, Chen CM, Chen FL, Lin PY, Hsiao YC, Wang PR, Su MT, Hsieh-Li HM, Hwang JC, Wu CH, Lee GC, Singh S, Lin Y, Hsieh SY, Lee-Chen GJ, Lin JY. (2009). Altered expression of HSPA5, HSPA8 and PARK7 in spinocerebellar ataxia type 17 identified by 2-dimensional fluorescence difference in gel electrophoresis. Clinica Chimica Acta, 400(1-2), 56-62.
  62. Wu CH, Jen PHS. (2009). Echo amplitude selectivity of the bat is better for expected than for unexpected echo duration. Neuroreport, 20(13), 1183-1187.
  63. Jen PH-S, Wu CH. (2008). Echo duration selectivity of the bat varies with pulse-echo amplitude difference. NeuroReport, 19(3), 373-377.
  64. Wu CH, Jen PH-S. (2008). Auditory frequency selectivity is better for expected than for unexpected sound duration. NeuroReport, 19(1), 127-131.
  65. Lin CW, Lin MY, Wu CH, Hwang HT, Fang K. (2008). VP-16-mediated Akt-Ser473 Dephosphorylation Induces Apoptosis in Human Non-small Cell Lung Cancer Cells with Mutated p53. BioFormosa, 1(43), 17-24
  66. Wu CH, Jen PHS. (2008). Echo frequency selectivity of duration-tuned inferior collicular neurons of the big brown bat, Eptesicus fuscus, determined with pulse-echo pairs. Neuroscience, 156(4), 1028-1038.
  67. Wu CH, Jen PH-S (2008) Bat inferior collicular neurons have the greatest frequency selectivity when determined with best-duration pulses. Neuroscience Letter, 438(3), 362-367.
  68. Wu CH, Jen PH-S. (2007). Neurons in the inferior colliculus of the big brown bat show maximal amplitude sensitivity at the best duration. Chinese Journal of Physiology, 50(5), 258-268.
  69. Wu CH, Jen PHS. (2006). The role of GABAergic inhibition in shaping duration selectivity of bat inferior collicular neurons determined with temporally patterned sound trains. Hearing Research, 215(1-2), 56-66.
  70. Wu CH, Jen PHS. (2006). GABA-mediated echo duration selectivity of inferior collicular neurons of Eptesicus fuscus, determined with single pulses and pulse-echo pairs. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 192(1), 985-1002.
  71. Yang SJ, Lee KZ, Wu CH, Lu KT, Hwang JC. (2006). Vasopressin produces inhibition on phrenic nerve activity and apnea through V1A receptors in the area postrema in rats. Chinese Journal of Physiology, 49(6), 1-13.
  72. Jen PHS, Wu CH. (2006). Duration selectivity organization in the inferior colliculus of the big brown bat, Eptesicus fuscus. Brain Research, 1108(1), 76-87.
  73. Jen PHS, Wu CH. (2005). The role of GABAergic inhibition in shaping the response size and duration selectivity of bat inferior collicular neurons to sound pulses in rapid sequences. Hearing Research, 202(1-2), 222-234.
  74. Tseng YL, Wu CH, Hwang JC. (2003). Arginine vasopressin reduces respiratory-related activity of the alae nasi muscle in rats. BioFormosa, 38(1), 37-47.
  75. Jen PHS, Wu CH, Luan RH, Zhou XM. (2002). GABAergic Inhibition contributes to pulse repetition rate-dependent frequency selectivity in the inferior colliculus of the big brown bat, Eptesicus fuscus. Brain Research, 948(1-2), 159-164.
  76. Jen PHS, Zhou XM, Wu CH. (2001). Temporally patterned pulse trains affect intensity and frequency sensitivity of inferior collicular neurons of the big brown bat, Eptesicus fuscus. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 187(8), 605-616.
  77. Yen CT, Hwang JC, Wu CH. (2000). Cardiac and ulmonary vagal neurons receive excitatory chemoreceptor input. Chinese Journal of Physiology, 43(1), 9-13.
  78. Wu CH, Hwang JC. (1997). Respiratory-related facial nerve activity in response to activation of the rostral ventrolateral medulla in the cats. Chinese Journal of Physiology, 40(2), 97-105.
  79. Wu CH, Hwang JC. (1996). Comparison of respiratory-related genioglossal activities with different breathing ways in response to dead space loading in the rats. Chinese Bioscience Association, 39(1), 9-18.
  80. Chuang HM, Wu CH, Hwang JC. (1996). Effect of aminophylline on respiratory genioglossus activity in the rats. Biological Bulletin of National Taiwan Normal University, 31(2), 141-148.

  1. Alternative Therapeutics of Chinese Herbal Medicine in Both Cell and Mouse Models of Alzheimer's Disease
  2. Wu CH* (2019) Alternative Therapeutics of Chinese Herbal Medicine in Both Cell and Mouse Models of Alzheimer's Disease. (2019 March 26-31, 14th International Conference on Alzheimer's & Parkinson's Diseases. Lisboa, Portugal)
  3. Wu CH* (2018) Comparative study of hypothermic adaptation mechanisms in bat's nervous system of Taiwan. (2018 November 1-4, 25th Congress of the Chinese Physiological Society, Nanchang, China)
  4. Wu CH* (2018) Innovative Technologies and Learning in Bat Echolocation. (2018-0827-30, ICITL2018/International Conference of Innovative Technologies and Learning 2018, Piran, Slovenia)
  5. Wu CH* (2018) The Impact of Neonics on Bats and Their Echolocation Systems. (2018-0629, 2018 TAIWAN Scientific Symposium on the Impact of & Alternatives to Systemic Pesticides, Taipei, Taiwan)
  6. Wu CH* (2018) Scientific Chinese medicine in Taiwan. (2018-0511, 2018 Traditional Chinese Medicine Forum of International Silk Road Fair, Xi'an, China)
  7. Wu CH*, Lin CL, Hsiao CJ, Hsu CH, Wang SE (2017) A neonicotinoid pesticide impairs echolocation systems in the insectivorous bat of Hipposideros armiger terasensis. (2017-1124~1201, Annual Meeting of Task Force on Systemic Pesticides, Padua, Italy)
  8. Wu CH*, Hsu CH, Wang SE, Lin CL, (2017) Alternative medicine of the herbal formula B401 in both cell and mouse models of Alzheimer's disease. (2017-0329~0402, The 13th International Conference on Alzheimer's & Parkinson's Diseases, Vienna, Austria)
  9. Wu CH*, Lin CL, Hsu CH, Wang SE, (2016) To Fly or Not To Fly- Whether Environmental Pollution Affects Bat Echolocation System. (2016-12-10~11: 3rd Annual Meeting of the Society for Bioacoustics, Aichi, Japan)
  10. Wu CH*, Sheu SJ, Hsu CH, Wang SE, Lin CL (2016) Therapeutic Potential of Chinese Herbal Medicine in Neurodegenerative Diseases. (2016-11-16~19: 14th Annual Congress of International Drug Discovery Science & Technology, Therapy and EXPO-2015, Nanjing, China)
  11. Wu CH*, Hsu CH, Wang SE, Lin CL, Sheu SJ, Oral treatment of the herbal formula B401 alleviates neuropsychiatric symptoms in transgenic mice of Alzheimer’s disease, 10th FENS Forum of Neuroscience, Copenhagen, Denmark
  12. Effects of traditional Chinese medicine B401 on erectile dysfunction in mice
  13. Traditional Chinese medicine B401 is ameliorative and neuroprotective in R6/2 mouse model of Huntington’s disease.

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109年度 【 利用臺灣特有藥用植物、天然物、微生物及其衍生物研發動物保健飼料添加劑之創新產發計畫 (3/3) 】 2020/06/01 2021/05/31 科技部(原國科會) MOST108-2321-B-003-001- 總主持人
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2018年TFSP國際研討會－系統性殺蟲劑的衝擊與替代方案 2018/06/28 2018/06/30 科技部(原國科會) 107-2916-I-003 -008 -A1 主持人
107利用臺灣特有藥用植物、天然物、微生物及其衍生物研發動物保健飼料添加劑之創新產發計畫(1/3) 2018/06/01 2019/05/31 科技部(原國科會) MOST 107-2321-B-003-001 - 總主持人
篩選可緩解巴金森氏症神經退化症狀的漢方藥物 2016/08/01 2017/07/31 科技部(原國科會) MOST 105-2320-B-003-001 - 主持人
科普活動：細胞科學影像之美 2015/08/01 2016/07/31 科技部(原國科會) MOST 104-2515-S-003-011~ 主持人
利用神經活細胞與基金轉殖小鼠模式發展保護神經中草藥的新穎篩選技術並探討中草藥緩解神經退化性疾病的保護機制-以阿茲海默氏症與亨丁頓舞蹈症為例 2015/08/01 2016/07/31 科技部(原國科會) MOST 104-2320-B-003-004- 主持人
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