1. “Composite Scores of Plasma Tau and β-Amyloids Correlate with Dementia in down Syndrome,” ACS Chemical Neuroscience, 11, 191-196, 2020. [IF:3.861,CHEMISTRY, MEDICAL:13/61=21.31%]
  2. “Blood NfL: A biomarker for disease severity and progression in Parkinson disease,” Neurology, 93, e1104-e1111, 2019. [IF:8.689,CLINICAL NEUROLOGY:10/199=5.0%; NEUROSCIENCE & BEHAVIOR:4/356=1.1%]
  3. “Characterizations of anti-alpha-fetoprotein- conjugated magnetic nanoparticles associated with alpha-fetoprotein for biomedical applications,” Sensors, 2017, 17, 2018. [IF:2.677, INSTRUMENTS & INSTRUMENTSTION:10/58 =17.2%]
  4. “Eight-Channel AC Magnetosusceptometer of Magnetic Nanoparticles for High-Throughput and Ultra-High-Sensitivity Immunoassay,” Sensors, 18, 1043, 2018. [IF:2.677, INSTRUMENTS & INSTRUMENTATION:10/58=17.2%](第一作者&通訊作者)
  5. “Plasma Biomarkers Differentiate Parkinson’s Disease From Atypical Parkinsonism Syndromes,” Frontiers in Aging Neuroscience, 10, 123, 2018. [IF:4.504, GERIATRICS&GERONTOLOGY: 7/49=14.3%; NEUROSCIENCES: 59/259=22.8%]
  6. “Bioassay using blocking temperature: Interparticle interactions between biofunctionalized magnetic nanoparticles conjugated with biotargets,” APPLIED PHYSICS LETTERS, 110, 133701,2017. [IF:3.142, PHYSICS,APPLIED: 28/145=19.3%]
  7. “Blood Beta-Amyloid and Tau in Down Syndrome: A Comparison with Alzheimer’s Disease,” Frontiers in Aging Neuroscience, 8, 316,2017. [IF:4.504, GERIATRICS&GERONTOLOGY: 7/49=14.3%; NEUROSCIENCES: 59/259=22.8%]
  8. “Plasma tau levels in cognitively normal middle-aged and older adults,” Frontiers in Aging Neuroscience, 9,51, 2017. [IF:4.504, GERIATRICS&GERONTOLOGY: 7/49=14.3%; NEUROSCIENCES: 59/259=22.8%]
  9. “Ultrasound-Induced Magnetic Imaging of Tumors Targeted by Biofunctional Magnetic Nanoparticles,” ACS Nano, 11, 3030–3037, 2017. [IF:13.942, CHEMISTRY, MULTIDISCPLINARY:9/166=5.4%; CHEMISTRY,PHYSICAL:5/146=3.4%; NANOSCIENCE & NANOTECHNOLOGY: 4/87=4.6%; MASTERIALS SCIENCE, MULTIDISPLINARY:9/275= 3.2%]
  10. “Plasma α-synuclein predicts cognitive decline in Parkinson's disease,” Journal of Neurology, Neurosurgery, and Psychiatry, 88, 818-824, 2017. [IF: 7.342, SURFERY: 3/200=1.5 %; CLINICAL NEUROLOGY: 12/193= 6.2 %;PSYCHIATRY 11/142 = 7.7%;]
  11. “Rapid and quantitative discrimination of tumour cells on tissue slices,” Nanotechnology,27, 235101,2016.(通訊作者) [IF: 3.440, Materials Science, Multidisplinary: 60/275=21.8%;Physics, Applied: 28/148=18.91%]
  12. “Development of an ultra-high sensitive immunoassay with plasma biomarker for differentiating Parkinson disease dementia from Parkinson disease using antibody functionalized magnetic nanoparticles,” J. Nanobiotechnol., 14,41, 2016. [IF:4.239, BIOTECHNOLOGY & APPLIED MICROBIOLOGY: 20/160=12.5%]
  13. “Immunomagnetic Reduction Assay on Desgammacarboxy Prothrombin for Screening of Hepatocellular Carcinoma,” IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 63, 1681, 2016.
  14. “SQUIDs in biomagnetism a roadmap towards improved healthcare,” Supercond. Sci. Technol., 29,113001, 2016. Topical Review. [IF: 2.878; Physics, Applied: 38/148=25.67 %]
  15. “Dual-Imaging Model of SQUID Biosusceptometry for Locating Tumors Targeted Using Magnetic Nanoparticles,” Journal of Nanobiotechnology, 13, 11, 2015. (第一作者&通訊作者) [IF:4.239, BIOTECHNOLOGY & APPLIED MICROBIOLOGY: 25/161=15.5%]
  16. “Sub-Tesla-field magnetization of vibrated magnetic nanoreagents for screening tumor markers,” Applied Physics Letters, 16, 073703, 2015. (第一作者&通訊作者) [IF:3.142, PHYSICS, APPLIED: 28/145=19.3%]
  17. “Novel Integration of an Ultrasound Probe and a Rotational-Scanning SQUID Biosusceptometer for Diagnosing Liver Tumors,” IEEE Trans. Appl.Supercond., 25, 1602704,2015. (第一作者&通訊作者) [IF: 1.041, ENGINEERING, ELECTRICAL & ELECTRONIC: 120/245=48.9%]
  18. “Assaying carcinoembryonic antigens by normalized saturation magnetization,” Nanoscale Research Letters, 10, 964, 2015. (通訊作者) [IF:2.584,ranking: 69/271=25.4% MATERIALS SCIENCE, MULTIDISCIPLINARY; 34/145=23.4% PHYSICS, APPLIED]
  19. “Magnetic Clustering Effect during the Association of Biofunctionalized Magnetic Nanoparticles with Biomarkers,” PLoS ONE, 10, e0135290,2015. (共同作者)[IF:3.234, MULTIDISCIPLINARY SCIENCES:9/57=15.7%]
  20. “Experimental study on thermal performances of heat pipes for air-conditioning systems influenced by magnetic nanofluids, external fields, and micro wicks,” International Journal of Refrigeration, 43, 62-70,2014. (通訊作者) [IF: 2.241, ENGINEERING, MECHANICAL: 15/130=11.5%]
  21. “ Plasma Tau as a Window to the Brain – Negative Associations with Brain Volume and Memory Function in Mild Cognitive Impairment and Early Alzheimer’s Disease,” Human Brain Mapping, 35,3132-3142, 2014. (共同作者) [IF: 6.924, RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING: 2/121=1.65%; NEUROIMAGING: 1/13=7.6% ;NEUROSCIENCES: 22/251=8.76%]
  22. “Using Bio-Functionalized Magnetic Nanoparticles and Dynamic Nuclear Magnetic Resonance to Characterize the Time-Dependent Spin-Spin Relaxation Time for Sensitive Bio-Detection,” Sensors,14, 21409-21417,2014. (共同作者)[IF:2.245, INSTRUMENTS & INSTRUMENTATION:10/56=17.8%]
  23. “Time-evolution Contrast of Target MRI Using High-stability Antibody Functionalized Magnetic Nanoparticles: An Animal Model,” Journal of Nanomaterials, 2014, 351848,2014. (共同作者) [IF: 1.611, MATERIALS SCIENCE, MULTIDISCIPLINARY: 104/251=41.4%]
  24. “Combined plasma biomarkers for diagnosing mild cognition impairment and Alzheimer’s disease,” ACS Chemical Neuroscience, 4,1530-1536, 2013. (共同作者) [IF: 3.871, CHEMISTRY, MEDICINAL:7/59=11.8%]
  25. “Time-dependent phase lag of biofunctionalized magnetic nanoparticles conjugated with biotargets studied with alternating current magnetic susceptometor for liquid phase immunoassays,” APPLIED PHYSICS LETTERS, 103, 243703, 2013. (共同作者) [IF: 3.794, PHYSICS, APPLIED: 20/128=15.6%]
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  28. “Anti-CEA-functionalized superparamagnetic iron oxide nanoparticles for examining colorectal tumors in vivo,” Nanoscale Research Letters, 8,413, 2013. (通訊作者) [IF:2.481,ranking: 53/251=21.1% MATERIALS SCIENCE, MULTIDISCIPLINARY; 31/136=22.7% PHYSICS, APPLIED]
  29. “Enhancing the tumor discrimination using antibody-activated magnetic nanoparticles in ultra-low magnetic fields,” APPLIED PHYSICS LETTERS, 102, 013119, 2013. (共同作者) [IF: 3.844, PHYSICS, APPLIED: 17/125=13.6%]
  30. “Microtesla NMR and High Resolution MR Imaging Using High-Tc SQUIDs ,” IEEE Trans. Appl.Supercond., 23, 1602404, 2013. (共同作者) [IF: 1.041, ENGINEERING, ELECTRICAL & ELECTRONIC: 120/245=48.9%]
  31. “Clinic Applications in Assaying Ultra-low concentration Bio-markers Using HTS SQUID-based AC Magnetosusceptometer” IEEE Trans. Appl.Supercond., 23, 1600604, 2013. (第二作者) [IF: 1.041, ENGINEERING, ELECTRICAL & ELECTRONIC: 120/245=48.9%]
  32. “Development for High-accuracy in-vitro Assay of Vascular Endothelial Growth Factor Using Nano-magnetically Labeled Immunoassay,” Journal of Nanomaterials, 2013, 695276, 2013. (共同作者) [IF: 1.547, MATERIALS SCIENCE, MULTIDISCIPLINARY:95/241=39.4%]
  33. “Experimental Study on Low-detection Limit for Immunomagnetic Reduction Assays by Manipulating Reagent Entities,” IEEE Transactions on Nanobioscience, 12, 65-68, 2013. (共同作者) [IF:1.28 NANOSCIENCE & NANOTECHNOLOGY: 43/66=65.1%]
  34. “Effect of molecule-particle binding on the reduction in the mixed-frequency ac magnetic susceptibility of magnetic bio-reagents,” JOURNAL of APPLIED PHYSICS, 112, 024704-1 -024704-4, 2012. (共同作者) [IF:2.168 PHYSICS, APPLIED: 37/125=29.6%]
  35. “New assay for old markers - plasma beta amyloid of mild cognitive impairment and Alzheimer’s disease,” Current Alzheimer Research, 9, 1142-1148, 2012. (共同作者) [IF:3.676, ranking: 17.8% CLINICAL NEUROLOGY]
  36. “A noninvasive method to determine the fate of Fe3O4 nanoparticles following intravenous injection using scanning SQUID biosusceptometry,” PLOS ONE, 7, e48510, 2012. (第二作者) [IF:4.09, ranking:14.1%, BIOLOGY]
  37. “Immunomagnetic reduction assay for nervous necrosis virus extracted from groupers,” Journal of Virological Methods, 181,68-72. 2012. (共同作者) [IF:2.011,ranking= 81/158=51.2%, BIOTECHNOLOGY & APPLIED MICROBIOLOGY ]
  38. “Universal behavior of bio-molecule-concentration dependent reduction in ac magnetic susceptibility of bio-reagents,” IEEE MAGNETICS LETTERS,3, 1500104, 2012.
  39. “In Vivo Screening of Hepatocellular Carcinoma Using the AC Susceptibility of Antialphafetoprotein-Activated Magnetic Nanoparticles,” PLOS ONE, 7, e46756, 2012. (第一作者) [IF:4.09, ranking:14.1%, BIOLOGY]
  40. “Use of a high-Tc SQUID-based nuclear magnetic resonance spectrometer in magnetically unshielded environments to discriminate tumors in rats, by characterizing the longitudinal relaxation rate,” Journal of Instrumentation, 7, P06005 , 2012. (共同作者) [IF:1.869 INSTRUMENTS & INSTRUMENTATION: 11/58=18.9%]
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  45. “Characteristics of magnetic labeling on liver tumors with anti-alpha-fetoprotein-mediated Fe3O4 magnetic nanoparticles,” International Journal of Nanomedicine, 7, 2987–2996, 2012. [IF:3.13, ranking: 26.8%, PHARMACOLOGY & PHARMACY ] (通訊作者&第二作者)
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  49. “Step –edge High-Tc SQUID Magnetometer for Low-Field Nuclear Magnetic Resonance,” IEEE Trans. Appl. Supercond. 21, 534-537(2011) (第三作者) [IF: 1.041, ENGINEERING, ELECTRICAL & ELECTRONIC: 120/245=48.9%]
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  52. “Non-invasive and High-sensitivity Scanning Detection of Magnetic Nanoparticles in Animals Using High-Tc Scanning Superconducting-Quantum-Interference- Device Biosusceptometry,” REVIEW OF SCIENTIFIC INSTRUMENTS,82, 084301, 2011.; 亦被選為Virtual Journal of Applications of Superconductivity -- August 15, 2011 (通訊作者&第一作者) [IF:1.367,ranking= 34.5%, INSTRUMENTS & INSTRUMENTATION]
  53. “In-vivo and real-time measurement of magnetic-nanoparticles distribution in animals by scanning SQUID Biosusceptometry for biomedicine study,” IEEE Transactions on Biomedical Engineering, 58, 2719 – 2724,2011. (第一作者) [IF:2.278,ranking= 22/72=30.5%, ENGINEERING, BIOMEDICAL]
  54. “Scanning Waveform Analysis of the Room-Temperature-Probe SQUID NDE System,” NDT & E INTERNATIONAL, 43, 586, 2010 . (第一作者) [IF: 1.446 MATERIALS SCIENCE, CHARACTERIZATION & TESTING 5/32=18.7%]
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名稱 開始日期 結束日期 委託單位 編號 參與身份別
魚刺精檢機工作站 - AIoT智慧終端裝置落地應用推廣 2021/11/01 2022/10/31 科技部(原國科會) 110-2622-E-003-004 主持人
開發具高專一性、快速治療、顯影的創新磁熱療術及兼具造影與治療的多功能系統II 2021/08/01 2022/07/31 科技部(原國科會) 109-2221-E-003 -005 -MY2 主持人
開發具高專一性、快速治療、顯影的創新磁熱療術及兼具造影與治療的多功能系統II 2020/08/01 2021/07/31 科技部(原國科會) 109-2221-E-003 -005 -MY2 主持人
產線離子濃度之線上分析系統 2020/06/01 2021/05/31 科技部(原國科會) 109-2622-E-003-002 -CC3 主持人
開發具高專一性、快速治療、顯影的創新磁熱療術及兼具造影與治療的多功能系統 2019/08/01 2020/07/31 科技部(原國科會) 108-2221-E-003 -006- 主持人
智慧型低電磁生物造影、治療與防護技術之人才培育與新創事業 2019/08/01 2020/07/31 教育部 主持人
超高靈敏度磁振造影暨高溫超導量子干涉元件之多模態動物癌症診斷平台--多通道高溫超導磁粒子造影系統之建構與特性研究 2018/08/01 2021/07/31 科技部(原國科會) 107-2314-B-003 -001 - ,108-2314-B-003 -001 -,109-2314-B-003 -004 - 協同/共同主持人
同步超音波結構造影與磁性功能性造影之創新技術開發 2018/08/01 2019/07/31 科技部(原國科會) 105-2628-E-003 -001 -MY3 主持人
光纖感測元組件與系統技術開發 2018/02/01 2021/01/31 科技部(原國科會) 107-2622-8-011-004-TE1,108-2622-8-011-003-TE1,109-2622-8-011 -014 -TE1 協同/共同主持人
同步超音波結構造影與磁性功能性造影之創新技術開發 2017/08/01 2018/07/31 科技部(原國科會) 105-2628-E-003 -001 -MY3 主持人
同步超音波結構造影與磁性功能性造影之創新技術開發 2016/08/01 2017/07/31 科技部(原國科會) 105-2628-E-003 -001 -MY3 主持人
創新磁超整合生醫造影術:技術開發、原型機建立 2015/08/01 2016/07/31 科技部(原國科會) 104-2221-E-003 -016 - 主持人
超靈敏8通道磁減量免疫檢測原型機開發 2014/11/01 2015/10/31 國科會 103-2321-B-003 -006 - 主持人
手術中即時造影磁性奈米粒子標靶的腫瘤之超導量子干涉儀系統開發 2013/08/01 2015/07/31 國科會 102-2221-E-003-008-MY2 主持人
開發高靈敏度、快篩、空間定位之高溫超導交流磁導儀以診斷被磁性奈米粒子標靶的肝癌 2012/08/01 2013/07/31 國科會 NSC 101-2221-E-003 -005 - 主持人
利用多重標靶磁性奈米試劑進行肝癌體外及體內診斷技術之開發 2012/01/01 2012/12/31 科技部(原國科會) DOH101-TD-N-111-004 協同/共同主持人
開發高靈敏度、非侵入式檢測動物的奈/微米鐵粒子之手持式生醫磁導儀 2011/08/01 2012/07/31 國科會 NSC 100-2221-E-003 -013 -  主持人
奈米標靶低磁場核磁共振造影與應用-標靶腫瘤鼠之代謝研究 2011/08/01 2012/07/31 國科會 100-2120-M002-015 協同/共同主持人
早期阿滋海默症之生物標記檢測技術研發與臨床應用開發 2011/05/01 2012/04/30 科技部(原國科會) DOH100-TD-PB-111-TM022 協同/共同主持人
磁性奈米粒子於肝癌及大腸癌體外早期免疫檢測與體內生化性標靶核磁共振造影之動物臨床應用研究 2011/01/01 2011/12/31 科技部(原國科會) DOH100-TD-N-111-008 協同/共同主持人
電磁波對磁性奈米粒子影響之物理模式及其應用於創新磁性生醫檢測架構之研究 2010/08/02 2011/07/31 國科會 98-2221-E-003-001-MY2 主持人
電磁波對磁性奈米粒子影響之物理模式及其應用於創新磁性生醫檢測架構之研究 2009/08/01 2010/08/01 國科會 98-2221-E-003-001-MY2 主持人
磁性奈米流體熱管之開發 2009/07/01 2010/06/30 國科會 98-2622-E-003-003-CC3 主持人
磁性標記免疫檢測試劑最佳化研究 2009/06/18 2010/07/17 國科會 98-2323-B-003-001-CC2 協同/共同主持人
磁性奈米粒子於阿滋海默症生物標記檢測之臨床研究 2009/03/01 2010/03/01 其他政府部門 98年度奈米國家型科技計畫 協同/共同主持人

  1. “Magnetic Tools for Medical Diagnosis,” Chapter 9 in “Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis,”[the 8th volume of SPRINGER book series] Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Germany, June 7, 2018. ISBN: 978-3-662-56332-8 (第一作者/通訊作者)